Biogeneticists open Pandora's box by tampering with the genes of several primates, which escape and breed in the California wilderness of Crater.
Several years later, Matt Hayden, an expeditionary biologist, is trapped by an earthquake in the remote Californian town during its annual reptile festival.
Along with his colleague Clancy Ryan and Dr Lauren Vale, the town's survivors are thrown into conflict with an arriving horde of hybrid apes, whose intelligence and breeding cycles have been genetically enhanced.
Fascinated by these creatures, Matt forms a tenuous relationship with the hybrids' leader, Kubla. However, relations between the two trapped species deteriorate, and Crater becomes an apocalyptic battleground in humanity's fight to remain the dominant species on earth.
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